NRF2 anticorps (C-Term)

N° du produit ABIN2792060

Cet anticorps anti-NRF2 est un anticorps Lapin Polyclonal détectant NRF2 dans WB. Adapté pour Humain, Rat, Chien, Porc, Boeuf (Vache), Cobaye, Lapin et Cheval.

Aperçu rapide pour NRF2 anticorps (C-Term) (ABIN2792060)

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Reactivité: Humain, Rat, Chien, Porc, Boeuf (Vache), Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NRF2 anticorps

Épitope: C-Term

Séquence: VSDLSLCKAF NQNHPESTAE FNDSDSGISL NTSPSVASPE HSVESSSYGD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against NFE2L2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NFE2L2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NRF2

Antigène: NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

Autre désignation: NFE2L2

Sujet: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: BACH1, HDAC3, WAC, FBXW11, KEAP1, TNNT1, MAPK7, HDAC2, HDAC1, MAFF, MAFG, MAFK, MAP2K2, MAP2K1, MAPK9, MAPK8, AKT1, UBC, NQO1, BRCA1, AHR, CREB3, NFE2L3, ENC1, SIAH2, NFE2, ATF4, Pparg, SUMO1, SUMO2, RNF4, BPTF, RBMX, KPNA3, SUMO3, MYC, DYT10, Ube2e1, PGA
Protein Size: 582

Poids moléculaire: 64 kDa

ID gène: 4780

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling